The olive tree (Olea europaea L.), its wood, fruit, leaves, roots and bark contain oleuropein, a non-toxic secoiridoid. It is a phenolic compound that has been shown to have various healing properties for vasodilator [1], hypotensive [2, 3], anti-inflammatory [4], antirheumatic [5], diuretic [6], anti-atherogenic [7]. ] and fever-reducing [8] effects. Most of these pharmacological properties of oleuropein (Figure 1) are due to its strong antioxidant effect [9].
Oleuropein appears to be present in olive tree parts. October olive leaves contain about 60~90 mg of oleuropein per gram (dry weight), in addition to significant levels of elenolic acid and Decoction of hydroxytyrosol (3,4-dihydrofenylethanol) glycosidic ester. However, oleuropein and its hydrolysis products oleuropein aglycone, elenolic acid, beta-3, 4-dihydroxyphenethyl alcohol and methyl-o-methyl elenolate turned out to be the main molecules of biological interest. The leaves are known to contain secoiridoids, including oleuropein, as well as ligustroside and oleacein. It also contains triterpenoids (oleanolic acid and uvaol), sterols, flavonoids (chrysoeriol, apigenin and luteolin glycosides) and various other phenolic acids [10].
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